In recent years, the health system of the country has been accompanied by various problems that caused dissatisfaction among the people and the various sectors of the health system. After the eleventh government emerged, the Ministry of Health and Medical Education developed a Health System Evolution Plan. The plan, which seeks to protect peoples’ financial against health costs, improving quality and access to health care, it was implemented in govermental hospitals across the country in April 2014. The current research was applied in terms of descriptive-cross-sectional method and using the questionnaire tool. Hence, the statistical population included citizen stakeholders in the development of the health system (doctors, people, and nurses). Based on the results of the data analysis in SPSS software, study showed that the appropriateness of assessing the Iranian physicians' knowledge of the Health System Evolution Plan was in the first rank with the average score of 2.98.  Moreover, the performance adequacy of the health insurance organizations in intergovernmental cooperation with the Ministry of Health and Medical Education in the implementation of the effectiveness of the Health System Evolution Plan was at 40th rank with an average of 1.50 points. In fact, it was indicatd that appropriatness of health insurance  organizations’ performances in Inter-departmental collaboration with the Ministry of Health and Medical Education was  considered as less importance for the implementation of the Health System Evolution Plan .