Designing based on principles of adult learning is an essential part of medical education. Accordingly, mortality and morbidity conference designed with inter professional education approach and CME score. After implementation, its satisfaction and acceptability and educational impact was assessed. This is a triangulation study. Monthly morbidity and mortality conferences with CME score was held during one year in 22ndBahman teaching hospital. The tools that be used were pre and post-tests and a satisfaction questionnaire developed by the researcher. Also a semi structured interview was done with 10 people who were participated in 5 or more conferences. Data was analyzed by SPSS software. Content analysis was done about interview transcripts. 202 medical professional people with average 37years old include 71%female and 29% male. 96% of participants have assessed attractiveness of these programs as very good. Pre and post-tests scores showed significant differences (p-value≤0.0001) and indicate increased of the learners' knowledge. In qualitative data analysis,95% of participants stated that will change their behavior, clinical reasoning and decision making. Also they found improvement in professional interpersonal communication, awareness of system based practice, effectiveness of inter professional education and learning from real errors, patient safety and quality of care as the positive outcome of it. High satisfaction that expressed by these medical professionals confirmed the effectiveness and fairness of the conferences.